Fluanxol
Brand names,
Fluanxol
Analogs
Fluanxol
Brand Names Mixture
Fluanxol
Chemical_Formula
C23H25F3N2OS
Fluanxol
RX_link
No information avaliable
Fluanxol
fda sheet
Fluanxol
msds (material safety sheet)
Fluanxol
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Fluanxol
Molecular Weight
434.519 g/mol
Fluanxol
Melting Point
No information avaliable
Fluanxol
H2O Solubility
0.000346 mg/ml
Fluanxol
State
Solid
Fluanxol
LogP
4.694
Fluanxol
Dosage Forms
Tablet; IM injection
Fluanxol
Indication
For use in the treatment of schizophrenia and depression
Fluanxol
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Fluanxol
Absorption
Fairly slow and incomplete after oral administration
Fluanxol
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Fluanxol
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Fluanxol
Organisms Affected
Humans and other mammals