Fluanxol Depot
Brand names,
Fluanxol Depot
Analogs
Fluanxol Depot
Brand Names Mixture
Fluanxol Depot
Chemical_Formula
C23H25F3N2OS
Fluanxol Depot
RX_link
No information avaliable
Fluanxol Depot
fda sheet
Fluanxol Depot
msds (material safety sheet)
Fluanxol Depot
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Fluanxol Depot
Molecular Weight
434.519 g/mol
Fluanxol Depot
Melting Point
No information avaliable
Fluanxol Depot
H2O Solubility
0.000346 mg/ml
Fluanxol Depot
State
Solid
Fluanxol Depot
LogP
4.694
Fluanxol Depot
Dosage Forms
Tablet; IM injection
Fluanxol Depot
Indication
For use in the treatment of schizophrenia and depression
Fluanxol Depot
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Fluanxol Depot
Absorption
Fairly slow and incomplete after oral administration
Fluanxol Depot
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Fluanxol Depot
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Fluanxol Depot
Organisms Affected
Humans and other mammals