Flupenthixole
Brand names,
Flupenthixole
Analogs
Flupenthixole
Brand Names Mixture
Flupenthixole
Chemical_Formula
C23H25F3N2OS
Flupenthixole
RX_link
No information avaliable
Flupenthixole
fda sheet
Flupenthixole
msds (material safety sheet)
Flupenthixole
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Flupenthixole
Molecular Weight
434.519 g/mol
Flupenthixole
Melting Point
No information avaliable
Flupenthixole
H2O Solubility
0.000346 mg/ml
Flupenthixole
State
Solid
Flupenthixole
LogP
4.694
Flupenthixole
Dosage Forms
Tablet; IM injection
Flupenthixole
Indication
For use in the treatment of schizophrenia and depression
Flupenthixole
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Flupenthixole
Absorption
Fairly slow and incomplete after oral administration
Flupenthixole
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Flupenthixole
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Flupenthixole
Organisms Affected
Humans and other mammals