Depix
Brand names,
Depix
Analogs
Depix
Brand Names Mixture
Depix
Chemical_Formula
C23H25F3N2OS
Depix
RX_link
No information avaliable
Depix
fda sheet
Depix
msds (material safety sheet)
Depix
Synthesis Reference
P. N. Craig, C. L. Zirkle, U.S. pat. 3,282,930 (1966 to SKF)
Depix
Molecular Weight
434.519 g/mol
Depix
Melting Point
No information avaliable
Depix
H2O Solubility
0.000346 mg/ml
Depix
State
Solid
Depix
LogP
4.694
Depix
Dosage Forms
Tablet; IM injection
Depix
Indication
For use in the treatment of schizophrenia and depression
Depix
Pharmacology
Flupenthixol is an anxiolytic, antidepressive agent and a mood stabilizer. It inhibits the central monoamine receptors, particularly the dopamine D1 and D2 receptors. Therefore, it increases the amount of serotonin and noradrenaline that control mood and thinking, and improves mood.
Depix
Absorption
Fairly slow and incomplete after oral administration
Depix
side effects and Toxicity
LD50=300 mk/kg (Oral in mice); LD50=791 mg/kg (Oral in rats); LD50=87 mk/kg (IV in mice); LD50=37 mg/kg (IV in rats)
Depix
Patient Information
Patient Information:
Flupenthixol alone or with alcohol may cause blurred vision or drowsiness. Avoid driving, operating machinery, or performing other
activities that may become hazardous because of decreased alertness. Patients should be warned not to drink alcohol while taking
Flupenthixol.
Patients should discuss about the risks of taking Flupenthixol to the fetus and child with the doctors if they are breastfeeding,
pregnant or thinking about becoming pregnant.
Patients should be advised to use sunscreen and wear protective clothing to avoid sunburn, because flupenthixol can cause your skin to
be more sensitive to sunlight than it is normally.
Depix
Organisms Affected
Humans and other mammals