Carbidopa
Categoria
Carbidopa Nombres de marca, Carbidopa Analogos
Carbidopa Marca los nombres de mezcla
Carbidopa Formula quimica
C10H14N2O4
Carbidopa RX enlace
http://www.rxlist.com/cgi/generic/sinemet.htm
Carbidopa FDA hoja
Carbidopa MSDS (hoja de seguridad de materiales)
Carbidopa Sintesis de referencia
Chemerda et al., Patente de EE.UU.. 3,462,536 (1963)
Carbidopa Peso molecular
226.229 g/mol
Carbidopa Punto de fusion
203-205oC
Carbidopa H2O Solubilidad
3,8 mg / L
Carbidopa Estado
Solid
Carbidopa LogP
0.494
Carbidopa Formas de dosificacion
Comprimido (25 mg)
Carbidopa Indicacion
Para el tratamiento de los síntomas de la enfermedad de Parkinson idiopática (parálisis agitante), parkinsonismo postencefalítico
Carbidopa Farmacologia
Carbidopa, un inhibidor de la descarboxilasa no competitivo, se utiliza en combinación con levodopa para el tratamiento de la enfermedad de Parkinson.
Carbidopa Absorcion
Descarboxila rápidamente en dopamina en los tejidos extracerebrales de modo que sólo una pequeña parte de la dosis administrada es transportado sin cambios en el sistema nervioso central.
Carbidopa Toxicidad
Los síntomas de una toxicidad carbidopa incluyen espasmos musculares o debilidad, espasmos de los párpados, náuseas, vómitos, diarrea, un latido irregular del corazón, confusión, agitación, alucinaciones y pérdida del conocimiento.
Carbidopa Informacion de Pacientes
Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Carbidopa Organismos afectados
Humanos y otros mamíferos
