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Zesulan Brand names, Zesulan Analogs

Zesulan Brand Names Mixture

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Zesulan Chemical_Formula


Zesulan RX_link

No information avaliable

Zesulan fda sheet

Zesulan msds (material safety sheet)

Zesulan Synthesis Reference

G. Gueremy et al., Ger. pat. 2,009,555 corresp to U.S. pat. 3,987,042 (1970, 1976 to Sogeras)

Zesulan Molecular Weight

322.468 g/mol

Zesulan Melting Point

130.5 oC

Zesulan H2O Solubility

No information avaliable

Zesulan State


Zesulan LogP


Zesulan Dosage Forms


Zesulan Indication

For the treatment of Hay fever, urticaria (hives) and allergic rhinitis

Zesulan Pharmacology

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Zesulan Absorption

No information avaliable

Zesulan side effects and Toxicity

No information avaliable

Zesulan Patient Information

No information avaliable

Zesulan Organisms Affected

Humans and other mammals