Virginan
Virginan Brand names, Virginan Analogs
Virginan Brand Names Mixture
- No information avaliable
Virginan Chemical_Formula
C20H22N2S
Virginan RX_link
No information avaliable
Virginan fda sheet
Virginan msds (material safety sheet)
Virginan Synthesis Reference
G. Gueremy et al., Ger. pat. 2,009,555 corresp to U.S. pat. 3,987,042 (1970, 1976 to Sogeras)
Virginan Molecular Weight
322.468 g/mol
Virginan Melting Point
130.5 oC
Virginan H2O Solubility
No information avaliable
Virginan State
Solid
Virginan LogP
5.119
Virginan Dosage Forms
Tablet
Virginan Indication
For the treatment of Hay fever, urticaria (hives) and allergic rhinitis
Virginan Pharmacology
In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Virginan Absorption
No information avaliable
Virginan side effects and Toxicity
No information avaliable
Virginan Patient Information
No information avaliable
Virginan Organisms Affected
Humans and other mammals
