Mequitazinum [Inn-Latin]

• Bronchodilator Agents
• Histamine H1 Antagonists
• ATC:R06AD07

• Butix
• Instotal
• Kitazemin
• Mequitazina
• Mequitazina [Inn-Spanish]
• Mequitazina [Spanish]
• Mequitazine [Ban:Dcf:Inn:Jan]
• Mequitazinum [Inn-Latin]
• Metaplexan
• Mircol
• Primalan
• Vigigan
• Virginan
• Zesulan

• No information avaliable

C₂₀H₂₂N₂S

No information avaliable

G. Gueremy et al., Ger. pat. 2,009,555 corresp to U.S. pat. 3,987,042 (1970, 1976 to Sogeras)

322.468 g/mol

130.5 ^oC

No information avaliable

Solid

5.119

Tablet

For the treatment of Hay fever, urticaria (hives) and allergic rhinitis

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H₁-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H₁-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

No information avaliable

No information avaliable

No information avaliable

Humans and other mammals