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Metaplexan Brand names, Metaplexan Analogs

Metaplexan Brand Names Mixture

  • No information avaliable

Metaplexan Chemical_Formula


Metaplexan RX_link

No information avaliable

Metaplexan fda sheet

Metaplexan msds (material safety sheet)

Metaplexan Synthesis Reference

G. Gueremy et al., Ger. pat. 2,009,555 corresp to U.S. pat. 3,987,042 (1970, 1976 to Sogeras)

Metaplexan Molecular Weight

322.468 g/mol

Metaplexan Melting Point

130.5 oC

Metaplexan H2O Solubility

No information avaliable

Metaplexan State


Metaplexan LogP


Metaplexan Dosage Forms


Metaplexan Indication

For the treatment of Hay fever, urticaria (hives) and allergic rhinitis

Metaplexan Pharmacology

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Metaplexan Absorption

No information avaliable

Metaplexan side effects and Toxicity

No information avaliable

Metaplexan Patient Information

No information avaliable

Metaplexan Organisms Affected

Humans and other mammals