Mequitazina en es it fr

Mequitazina Brand names, Mequitazina Analogs

Mequitazina Brand Names Mixture

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Mequitazina Chemical_Formula


Mequitazina RX_link

No information avaliable

Mequitazina fda sheet

Mequitazina msds (material safety sheet)

Mequitazina Synthesis Reference

G. Gueremy et al., Ger. pat. 2,009,555 corresp to U.S. pat. 3,987,042 (1970, 1976 to Sogeras)

Mequitazina Molecular Weight

322.468 g/mol

Mequitazina Melting Point

130.5 oC

Mequitazina H2O Solubility

No information avaliable

Mequitazina State


Mequitazina LogP


Mequitazina Dosage Forms


Mequitazina Indication

For the treatment of Hay fever, urticaria (hives) and allergic rhinitis

Mequitazina Pharmacology

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Mequitazina Absorption

No information avaliable

Mequitazina side effects and Toxicity

No information avaliable

Mequitazina Patient Information

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Mequitazina Organisms Affected

Humans and other mammals