Vinorelbine Tartrate
Vinorelbine Tartrate Brand names, Vinorelbine Tartrate Analogs
Vinorelbine Tartrate Brand Names Mixture
- No information avaliable
Vinorelbine Tartrate Chemical_Formula
C45H54N4O8
Vinorelbine Tartrate RX_link
http://www.rxlist.com/cgi/generic2/vinor.htm
Vinorelbine Tartrate fda sheet
Vinorelbine Tartrate msds (material safety sheet)
Vinorelbine Tartrate Synthesis Reference
No information avaliable
Vinorelbine Tartrate Molecular Weight
778.932 g/mol
Vinorelbine Tartrate Melting Point
No information avaliable
Vinorelbine Tartrate H2O Solubility
No information avaliable
Vinorelbine Tartrate State
Solid
Vinorelbine Tartrate LogP
5.829
Vinorelbine Tartrate Dosage Forms
Solution
Vinorelbine Tartrate Indication
For the treatment of non-small-cell lung carcinoma
Vinorelbine Tartrate Pharmacology
Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.
Vinorelbine Tartrate Absorption
No information avaliable
Vinorelbine Tartrate side effects and Toxicity
No information avaliable
Vinorelbine Tartrate Patient Information
No information avaliable
Vinorelbine Tartrate Organisms Affected
Humans and other mammals
