Vinorelbine Bitartrate
Vinorelbine Bitartrate Brand names, Vinorelbine Bitartrate Analogs
Vinorelbine Bitartrate Brand Names Mixture
- No information avaliable
Vinorelbine Bitartrate Chemical_Formula
C45H54N4O8
Vinorelbine Bitartrate RX_link
http://www.rxlist.com/cgi/generic2/vinor.htm
Vinorelbine Bitartrate fda sheet
Vinorelbine Bitartrate msds (material safety sheet)
Vinorelbine Bitartrate Synthesis Reference
No information avaliable
Vinorelbine Bitartrate Molecular Weight
778.932 g/mol
Vinorelbine Bitartrate Melting Point
No information avaliable
Vinorelbine Bitartrate H2O Solubility
No information avaliable
Vinorelbine Bitartrate State
Solid
Vinorelbine Bitartrate LogP
5.829
Vinorelbine Bitartrate Dosage Forms
Solution
Vinorelbine Bitartrate Indication
For the treatment of non-small-cell lung carcinoma
Vinorelbine Bitartrate Pharmacology
Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.
Vinorelbine Bitartrate Absorption
No information avaliable
Vinorelbine Bitartrate side effects and Toxicity
No information avaliable
Vinorelbine Bitartrate Patient Information
No information avaliable
Vinorelbine Bitartrate Organisms Affected
Humans and other mammals
