Vinorelbine Bitartrate en es it fr

Vinorelbine Bitartrate Brand names, Vinorelbine Bitartrate Analogs

Vinorelbine Bitartrate Brand Names Mixture

  • No information avaliable

Vinorelbine Bitartrate Chemical_Formula

C45H54N4O8

Vinorelbine Bitartrate RX_link

http://www.rxlist.com/cgi/generic2/vinor.htm

Vinorelbine Bitartrate fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=136

Vinorelbine Bitartrate msds (material safety sheet)

Vinorelbine Bitartrate Synthesis Reference

No information avaliable

Vinorelbine Bitartrate Molecular Weight

778.932 g/mol

Vinorelbine Bitartrate Melting Point

No information avaliable

Vinorelbine Bitartrate H2O Solubility

No information avaliable

Vinorelbine Bitartrate State

Solid

Vinorelbine Bitartrate LogP

5.829

Vinorelbine Bitartrate Dosage Forms

Solution

Vinorelbine Bitartrate Indication

For the treatment of non-small-cell lung carcinoma

Vinorelbine Bitartrate Pharmacology

Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vinorelbine Bitartrate Absorption

No information avaliable

Vinorelbine Bitartrate side effects and Toxicity

No information avaliable

Vinorelbine Bitartrate Patient Information

No information avaliable

Vinorelbine Bitartrate Organisms Affected

Humans and other mammals