Vinorelbine Ditartrate
Vinorelbine Ditartrate Brand names, Vinorelbine Ditartrate Analogs
Vinorelbine Ditartrate Brand Names Mixture
- No information avaliable
Vinorelbine Ditartrate Chemical_Formula
C45H54N4O8
Vinorelbine Ditartrate RX_link
http://www.rxlist.com/cgi/generic2/vinor.htm
Vinorelbine Ditartrate fda sheet
Vinorelbine Ditartrate msds (material safety sheet)
Vinorelbine Ditartrate Synthesis Reference
No information avaliable
Vinorelbine Ditartrate Molecular Weight
778.932 g/mol
Vinorelbine Ditartrate Melting Point
No information avaliable
Vinorelbine Ditartrate H2O Solubility
No information avaliable
Vinorelbine Ditartrate State
Solid
Vinorelbine Ditartrate LogP
5.829
Vinorelbine Ditartrate Dosage Forms
Solution
Vinorelbine Ditartrate Indication
For the treatment of non-small-cell lung carcinoma
Vinorelbine Ditartrate Pharmacology
Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.
Vinorelbine Ditartrate Absorption
No information avaliable
Vinorelbine Ditartrate side effects and Toxicity
No information avaliable
Vinorelbine Ditartrate Patient Information
No information avaliable
Vinorelbine Ditartrate Organisms Affected
Humans and other mammals
