Vinorelbine Ditartrate en es it fr

Vinorelbine Ditartrate Brand names, Vinorelbine Ditartrate Analogs

Vinorelbine Ditartrate Brand Names Mixture

  • No information avaliable

Vinorelbine Ditartrate Chemical_Formula

C45H54N4O8

Vinorelbine Ditartrate RX_link

http://www.rxlist.com/cgi/generic2/vinor.htm

Vinorelbine Ditartrate fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=136

Vinorelbine Ditartrate msds (material safety sheet)

Vinorelbine Ditartrate Synthesis Reference

No information avaliable

Vinorelbine Ditartrate Molecular Weight

778.932 g/mol

Vinorelbine Ditartrate Melting Point

No information avaliable

Vinorelbine Ditartrate H2O Solubility

No information avaliable

Vinorelbine Ditartrate State

Solid

Vinorelbine Ditartrate LogP

5.829

Vinorelbine Ditartrate Dosage Forms

Solution

Vinorelbine Ditartrate Indication

For the treatment of non-small-cell lung carcinoma

Vinorelbine Ditartrate Pharmacology

Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vinorelbine Ditartrate Absorption

No information avaliable

Vinorelbine Ditartrate side effects and Toxicity

No information avaliable

Vinorelbine Ditartrate Patient Information

No information avaliable

Vinorelbine Ditartrate Organisms Affected

Humans and other mammals