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Navelbine Brand names, Navelbine Analogs

Navelbine Brand Names Mixture

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Navelbine Chemical_Formula


Navelbine RX_link

Navelbine fda sheet

Navelbine msds (material safety sheet)

Navelbine Synthesis Reference

No information avaliable

Navelbine Molecular Weight

778.932 g/mol

Navelbine Melting Point

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Navelbine H2O Solubility

No information avaliable

Navelbine State


Navelbine LogP


Navelbine Dosage Forms


Navelbine Indication

For the treatment of non-small-cell lung carcinoma

Navelbine Pharmacology

Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Navelbine Absorption

No information avaliable

Navelbine side effects and Toxicity

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Navelbine Patient Information

No information avaliable

Navelbine Organisms Affected

Humans and other mammals