Navelbine Base en es it fr

Navelbine Base Brand names, Navelbine Base Analogs

Navelbine Base Brand Names Mixture

  • No information avaliable

Navelbine Base Chemical_Formula

C45H54N4O8

Navelbine Base RX_link

http://www.rxlist.com/cgi/generic2/vinor.htm

Navelbine Base fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=136

Navelbine Base msds (material safety sheet)

Navelbine Base Synthesis Reference

No information avaliable

Navelbine Base Molecular Weight

778.932 g/mol

Navelbine Base Melting Point

No information avaliable

Navelbine Base H2O Solubility

No information avaliable

Navelbine Base State

Solid

Navelbine Base LogP

5.829

Navelbine Base Dosage Forms

Solution

Navelbine Base Indication

For the treatment of non-small-cell lung carcinoma

Navelbine Base Pharmacology

Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Navelbine Base Absorption

No information avaliable

Navelbine Base side effects and Toxicity

No information avaliable

Navelbine Base Patient Information

No information avaliable

Navelbine Base Organisms Affected

Humans and other mammals