Vinorelbina [Spanish] en es it fr

Vinorelbina [Spanish] Brand names, Vinorelbina [Spanish] Analogs

Vinorelbina [Spanish] Brand Names Mixture

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Vinorelbina [Spanish] Chemical_Formula


Vinorelbina [Spanish] RX_link

Vinorelbina [Spanish] fda sheet

Vinorelbina [Spanish] msds (material safety sheet)

Vinorelbina [Spanish] Synthesis Reference

No information avaliable

Vinorelbina [Spanish] Molecular Weight

778.932 g/mol

Vinorelbina [Spanish] Melting Point

No information avaliable

Vinorelbina [Spanish] H2O Solubility

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Vinorelbina [Spanish] State


Vinorelbina [Spanish] LogP


Vinorelbina [Spanish] Dosage Forms


Vinorelbina [Spanish] Indication

For the treatment of non-small-cell lung carcinoma

Vinorelbina [Spanish] Pharmacology

Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vinorelbina [Spanish] Absorption

No information avaliable

Vinorelbina [Spanish] side effects and Toxicity

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Vinorelbina [Spanish] Patient Information

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Vinorelbina [Spanish] Organisms Affected

Humans and other mammals