Vinorelbine Ditartarate
Vinorelbine Ditartarate Brand names, Vinorelbine Ditartarate Analogs
Vinorelbine Ditartarate Brand Names Mixture
- No information avaliable
Vinorelbine Ditartarate Chemical_Formula
C45H54N4O8
Vinorelbine Ditartarate RX_link
http://www.rxlist.com/cgi/generic2/vinor.htm
Vinorelbine Ditartarate fda sheet
Vinorelbine Ditartarate msds (material safety sheet)
Vinorelbine Ditartarate Synthesis Reference
No information avaliable
Vinorelbine Ditartarate Molecular Weight
778.932 g/mol
Vinorelbine Ditartarate Melting Point
No information avaliable
Vinorelbine Ditartarate H2O Solubility
No information avaliable
Vinorelbine Ditartarate State
Solid
Vinorelbine Ditartarate LogP
5.829
Vinorelbine Ditartarate Dosage Forms
Solution
Vinorelbine Ditartarate Indication
For the treatment of non-small-cell lung carcinoma
Vinorelbine Ditartarate Pharmacology
Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.
Vinorelbine Ditartarate Absorption
No information avaliable
Vinorelbine Ditartarate side effects and Toxicity
No information avaliable
Vinorelbine Ditartarate Patient Information
No information avaliable
Vinorelbine Ditartarate Organisms Affected
Humans and other mammals
