Vinorelbine Ditartarate en es it fr

Vinorelbine Ditartarate Brand names, Vinorelbine Ditartarate Analogs

Vinorelbine Ditartarate Brand Names Mixture

  • No information avaliable

Vinorelbine Ditartarate Chemical_Formula

C45H54N4O8

Vinorelbine Ditartarate RX_link

http://www.rxlist.com/cgi/generic2/vinor.htm

Vinorelbine Ditartarate fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=136

Vinorelbine Ditartarate msds (material safety sheet)

Vinorelbine Ditartarate Synthesis Reference

No information avaliable

Vinorelbine Ditartarate Molecular Weight

778.932 g/mol

Vinorelbine Ditartarate Melting Point

No information avaliable

Vinorelbine Ditartarate H2O Solubility

No information avaliable

Vinorelbine Ditartarate State

Solid

Vinorelbine Ditartarate LogP

5.829

Vinorelbine Ditartarate Dosage Forms

Solution

Vinorelbine Ditartarate Indication

For the treatment of non-small-cell lung carcinoma

Vinorelbine Ditartarate Pharmacology

Vinorelbine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vinorelbine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vinorelbine Ditartarate Absorption

No information avaliable

Vinorelbine Ditartarate side effects and Toxicity

No information avaliable

Vinorelbine Ditartarate Patient Information

No information avaliable

Vinorelbine Ditartarate Organisms Affected

Humans and other mammals