Valaciclovir Hydrochloride en es it fr

Valaciclovir Hydrochloride Brand names, Valaciclovir Hydrochloride Analogs

Valaciclovir Hydrochloride Brand Names Mixture

  • No information avaliable

Valaciclovir Hydrochloride Chemical_Formula

C13H20N6O4

Valaciclovir Hydrochloride RX_link

http://www.rxlist.com/cgi/generic3/valacyclovir.htm

Valaciclovir Hydrochloride fda sheet

Valaciclovir_Hydrochloride FDA

Valaciclovir Hydrochloride msds (material safety sheet)

Valaciclovir_Hydrochloride MSDS

Valaciclovir Hydrochloride Synthesis Reference

No information avaliable

Valaciclovir Hydrochloride Molecular Weight

324.336 g/mol

Valaciclovir Hydrochloride Melting Point

No information avaliable

Valaciclovir Hydrochloride H2O Solubility

No information avaliable

Valaciclovir Hydrochloride State

Solid

Valaciclovir Hydrochloride LogP

No information avaliable

Valaciclovir Hydrochloride Dosage Forms

Tablet

Valaciclovir Hydrochloride Indication

For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals.

Valaciclovir Hydrochloride Pharmacology

Valacyclovir is a prodrug and synthetic purine nucleoside analogue with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is almost completely converted to acyclovir and L-valine. The inhibitory activity of valacyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, which is then converted into acyclovir diphosphate and triphosphate by cellular enzymes. Acyclovir is selectively converted to the active triphosphate form by cells infected with herpes viruses.

Valaciclovir Hydrochloride Absorption

After oral administration, valacyclovir hydrochloride is rapidly absorbed from the gastrointestinal tract. The absolute bioavailability of acyclovir after administration of valacyclovir is 54.5% ± 9.1%.

Valaciclovir Hydrochloride side effects and Toxicity

Adverse effects of overexposure might include headache and nausea.

Valaciclovir Hydrochloride Patient Information

Valaciclovir Hydrochloride Organisms Affected

Human herpes virus