Valacyclovir Hydrochloride en es it fr

Valacyclovir Hydrochloride Brand names, Valacyclovir Hydrochloride Analogs

Valacyclovir Hydrochloride Brand Names Mixture

  • No information avaliable

Valacyclovir Hydrochloride Chemical_Formula

C13H20N6O4

Valacyclovir Hydrochloride RX_link

http://www.rxlist.com/cgi/generic3/valacyclovir.htm

Valacyclovir Hydrochloride fda sheet

Valacyclovir_Hydrochloride FDA

Valacyclovir Hydrochloride msds (material safety sheet)

Valacyclovir_Hydrochloride MSDS

Valacyclovir Hydrochloride Synthesis Reference

No information avaliable

Valacyclovir Hydrochloride Molecular Weight

324.336 g/mol

Valacyclovir Hydrochloride Melting Point

No information avaliable

Valacyclovir Hydrochloride H2O Solubility

No information avaliable

Valacyclovir Hydrochloride State

Solid

Valacyclovir Hydrochloride LogP

No information avaliable

Valacyclovir Hydrochloride Dosage Forms

Tablet

Valacyclovir Hydrochloride Indication

For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals.

Valacyclovir Hydrochloride Pharmacology

Valacyclovir is a prodrug and synthetic purine nucleoside analogue with inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Valacyclovir is almost completely converted to acyclovir and L-valine. The inhibitory activity of valacyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. This viral enzyme converts acyclovir into acyclovir monophosphate, which is then converted into acyclovir diphosphate and triphosphate by cellular enzymes. Acyclovir is selectively converted to the active triphosphate form by cells infected with herpes viruses.

Valacyclovir Hydrochloride Absorption

After oral administration, valacyclovir hydrochloride is rapidly absorbed from the gastrointestinal tract. The absolute bioavailability of acyclovir after administration of valacyclovir is 54.5% ± 9.1%.

Valacyclovir Hydrochloride side effects and Toxicity

Adverse effects of overexposure might include headache and nausea.

Valacyclovir Hydrochloride Patient Information

Valacyclovir Hydrochloride Organisms Affected

Human herpes virus