Tropic acid, ester with tropine
Tropic acid, ester with tropine Brand names, Tropic acid, ester with tropine Analogs
- Atnaa
- Atropair
- Atropen
- Atropin
- Atropin [German]
- Atropin-flexiolen
- Atropina
- Atropina [Italian]
- Atropine Care
- Atropine Sulfate
- Atropine Sulfate Ansyr Plastic Syringe
- Atropine Sulfate S.O.P.
- Atropinol
- Atropisol
- Atrosulf
- DL-Hyoscyamine
- DL-Tropyl tropate
- Equipin
- Eyesules
- Homapin-10
- Homapin-5
- Hyoscyamine
- I-Tropine
- Isopto Atropine
- Isopto-atropine
- Minims Atropine
- Ocu-Tropine
- Protamine + Atropine
- Protamine and Atropine
- Tropic acid, ester with tropine
- Tropine tropate
- Troyl tropate
Tropic acid, ester with tropine Brand Names Mixture
- No information avaliable
Tropic acid, ester with tropine Chemical_Formula
C17H23NO3
Tropic acid, ester with tropine RX_link
http://www.rxlist.com/cgi/generic3/atropen.htm
Tropic acid, ester with tropine fda sheet
Tropic acid, ester with tropine msds (material safety sheet)
Tropic acid, ester with tropine Synthesis Reference
No information avaliable
Tropic acid, ester with tropine Molecular Weight
289.369 g/mol
Tropic acid, ester with tropine Melting Point
118.5 oC
Tropic acid, ester with tropine H2O Solubility
Highly soluble (2200 mg/L)
Tropic acid, ester with tropine State
Solid
Tropic acid, ester with tropine LogP
2.904
Tropic acid, ester with tropine Dosage Forms
Drops; Liquid; Ointment; Solution
Tropic acid, ester with tropine Indication
For the treatment of poisoning by susceptible organophosphorous nerve agents having cholinesterase activity as well as organophosphorous or carbamate insecticides.
Tropic acid, ester with tropine Pharmacology
Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and l-hyoscyamine, whose activity is due almost entirely to the levo isomer of the drug. Atropine is commonly classified as an anticholinergic or antiparasympathetic (parasympatholytic) drug. More precisely, however, it is termed an antimuscarinic agent since it antagonizes the muscarine-like actions of acetylcholine and other choline esters. Adequate doses of atropine abolish various types of reflex vagal cardiac slowing or asystole. The drug also prevents or abolishes bradycardia or asystole produced by injection of choline esters, anticholinesterase agents or other parasympathomimetic drugs, and cardiac arrest produced by stimulation of the vagus. Atropine may also lessen the degree of partial heart block when vagal activity is an etiologic factor. Atropine in clinical doses counteracts the peripheral dilatation and abrupt decrease in blood pressure produced by choline esters. However, when given by itself, atropine does not exert a striking or uniform effect on blood vessels or blood pressure.
Tropic acid, ester with tropine Absorption
Atropine is rapidly and well absorbed after intramuscular administration. Atropine disappears rapidly from the blood and is distributed throughout the various body tissues and fluids.
Tropic acid, ester with tropine side effects and Toxicity
Oral, mouse: LD50 = 75 mg/kg. Symptoms of overdose includes widespread paralysis of parasympathetically innervated organs. Dry mucous membranes, widely dilated and nonresponsive pupils, tachycardia, fever and cutaneous flush are especially prominent, as are mental and neurological symptoms. In instances of severe intoxication, respiratory depression, coma, circulatory collapse and death may occur.
Tropic acid, ester with tropine Patient Information
Tropic acid, ester with tropine Organisms Affected
Humans and other mammals
