Triamterene
Brand names,
Triamterene
Analogs
Triamterene
Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Triamterene
Chemical_Formula
C12H11N7
Triamterene
RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Triamterene
fda sheet
Triamterene
msds (material safety sheet)
Triamterene
Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Triamterene
Molecular Weight
253.263 g/mol
Triamterene
Melting Point
316 oC
Triamterene
H2O Solubility
48.2 mg/L
Triamterene
State
Solid
Triamterene
LogP
-0.323
Triamterene
Dosage Forms
Tablet
Triamterene
Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Triamterene
Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Triamterene
Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Triamterene
side effects and Toxicity
No information avaliable
Triamterene
Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of
increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Triamterene
Organisms Affected
Humans and other mammals