Tri-Span
Tri-Span Brand names, Tri-Span Analogs
Tri-Span Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Tri-Span Chemical_Formula
C12H11N7
Tri-Span RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Tri-Span fda sheet
Tri-Span msds (material safety sheet)
Tri-Span Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Tri-Span Molecular Weight
253.263 g/mol
Tri-Span Melting Point
316 oC
Tri-Span H2O Solubility
48.2 mg/L
Tri-Span State
Solid
Tri-Span LogP
-0.323
Tri-Span Dosage Forms
Tablet
Tri-Span Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Tri-Span Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Tri-Span Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Tri-Span side effects and Toxicity
No information avaliable
Tri-Span Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Tri-Span Organisms Affected
Humans and other mammals
