Diurene
Diurene Brand names, Diurene Analogs
Diurene Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Diurene Chemical_Formula
C12H11N7
Diurene RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Diurene fda sheet
Diurene msds (material safety sheet)
Diurene Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Diurene Molecular Weight
253.263 g/mol
Diurene Melting Point
316 oC
Diurene H2O Solubility
48.2 mg/L
Diurene State
Solid
Diurene LogP
-0.323
Diurene Dosage Forms
Tablet
Diurene Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Diurene Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Diurene Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Diurene side effects and Toxicity
No information avaliable
Diurene Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Diurene Organisms Affected
Humans and other mammals
