Trispan
Trispan Brand names, Trispan Analogs
Trispan Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Trispan Chemical_Formula
C12H11N7
Trispan RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Trispan fda sheet
Trispan msds (material safety sheet)
Trispan Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Trispan Molecular Weight
253.263 g/mol
Trispan Melting Point
316 oC
Trispan H2O Solubility
48.2 mg/L
Trispan State
Solid
Trispan LogP
-0.323
Trispan Dosage Forms
Tablet
Trispan Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Trispan Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Trispan Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Trispan side effects and Toxicity
No information avaliable
Trispan Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Trispan Organisms Affected
Humans and other mammals
