Triamteril
Brand names,
Triamteril
Analogs
Triamteril
Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Triamteril
Chemical_Formula
C12H11N7
Triamteril
RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Triamteril
fda sheet
Triamteril
msds (material safety sheet)
Triamteril
Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Triamteril
Molecular Weight
253.263 g/mol
Triamteril
Melting Point
316 oC
Triamteril
H2O Solubility
48.2 mg/L
Triamteril
State
Solid
Triamteril
LogP
-0.323
Triamteril
Dosage Forms
Tablet
Triamteril
Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Triamteril
Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Triamteril
Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Triamteril
side effects and Toxicity
No information avaliable
Triamteril
Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of
increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Triamteril
Organisms Affected
Humans and other mammals