Diren
Diren Brand names, Diren Analogs
Diren Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Diren Chemical_Formula
C12H11N7
Diren RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Diren fda sheet
Diren msds (material safety sheet)
Diren Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Diren Molecular Weight
253.263 g/mol
Diren Melting Point
316 oC
Diren H2O Solubility
48.2 mg/L
Diren State
Solid
Diren LogP
-0.323
Diren Dosage Forms
Tablet
Diren Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Diren Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Diren Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Diren side effects and Toxicity
No information avaliable
Diren Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Diren Organisms Affected
Humans and other mammals
