Noridyl
Brand names,
Noridyl
Analogs
Noridyl
Brand Names Mixture
- Apo Triazide Tab (Hydrochlorothiazide + Triamterene)
- Dyazide Tab (Hydrochlorothiazide + Triamterene)
- Novo-Triamzide (Hydrochlorothiazide + Triamterene)
- Nu-Triazide Tab 50 Mg/25 Mg (Hydrochlorothiazide + Triamterene)
- Penta-Triamterene HCTZ Tablets (Hydrochlorothiazide + Triamterene)
- Pro-Triazide (Hydrochlorothiazide + Triamterene)
- Riva-Zide 50/25mg Tablets (Hydrochlorothiazide + Triamterene)
Noridyl
Chemical_Formula
C12H11N7
Noridyl
RX_link
http://www.rxlist.com/cgi/generic/triamterine.htm
Noridyl
fda sheet
Noridyl
msds (material safety sheet)
Noridyl
Synthesis Reference
Spickett, Timmis, J. Chem.. Soc. 1954, 2887 (1958)
Noridyl
Molecular Weight
253.263 g/mol
Noridyl
Melting Point
316 oC
Noridyl
H2O Solubility
48.2 mg/L
Noridyl
State
Solid
Noridyl
LogP
-0.323
Noridyl
Dosage Forms
Tablet
Noridyl
Indication
For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism.
Noridyl
Pharmacology
Triamterene, a relatively weak, potassium-sparing distal tubule diuretic and antihypertensive, is used in the management of hypokalemia. Triamterene is similar in action to amiloride but, unlike amiloride, increases the urinary excretion of magnesium.
Noridyl
Absorption
Rapidly absorbed, with somewhat less than 50% of the oral dose reaching the urine.
Noridyl
side effects and Toxicity
No information avaliable
Noridyl
Patient Information
Information for Patients
To help avoid stomach upset, it is recommended that the drug be taken after meals.
If a single daily dose is prescribed, it may be preferable to take it in the morning to minimize the effect of
increased frequency of urination on nighttime sleep.
If a dose is missed, the patient should not take more than the prescribed dose at the next dosing interval.
Noridyl
Organisms Affected
Humans and other mammals