Tabalon
Brand names,
Tabalon
Analogs
Tabalon
Brand Names Mixture
- Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
- Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
Tabalon
Chemical_Formula
C13H18O2
Tabalon
RX_link
http://www.rxlist.com/cgi/generic/ibup.htm
Tabalon
fda sheet
Tabalon
msds (material safety sheet)
Tabalon
Synthesis Reference
Nicholson, Adams; U.S. Pat. 3,228,831 (1966)
Tabalon
Molecular Weight
206.281 g/mol
Tabalon
Melting Point
75 - 77 oC
Tabalon
H2O Solubility
0.049 mg/ml
Tabalon
State
Solid
Tabalon
LogP
3.481
Tabalon
Dosage Forms
Tablet; Suspension
Tabalon
Indication
For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia
Tabalon
Pharmacology
Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ibuprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.
Tabalon
Absorption
rapidly absorbed
Tabalon
side effects and Toxicity
Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting; LD50=1255mg/kg(orally in mice)
Tabalon
Patient Information
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, reduce fever,
and treat osteoarthritis, rheumatoid arthritis, and menstrual cramps. Inform your physician if you are pregnant or
nursing. Ibuprofen should not be taken during the last three months of pregnancy. Inform your physician if you use
alcohol chronically. Ibuprofen should not be taken with aspirin products. This medication should be taken with food,
milk or antacids if stomach upset occurs. Ibuprofen may cause dizziness and drowsiness; use caution while driving or
operating hazardous machinery. Ibuprofen may cause increased sensitivity to sunlight. Use sunscreens and wear
protective clothing until degree of sensitivity is determined. Notify your physician if you develop stomach pain,
bloody vomit, bloody or black tarry stools, cloudy urine, trouble breathing, rash or hives.
Tabalon
Organisms Affected
Humans and other mammals