Pediatric Advil
Brand names,
Pediatric Advil
Analogs
Pediatric Advil
Brand Names Mixture
- Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
- Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
Pediatric Advil
Chemical_Formula
C13H18O2
Pediatric Advil
RX_link
http://www.rxlist.com/cgi/generic/ibup.htm
Pediatric Advil
fda sheet
Pediatric Advil
msds (material safety sheet)
Pediatric Advil
Synthesis Reference
Nicholson, Adams; U.S. Pat. 3,228,831 (1966)
Pediatric Advil
Molecular Weight
206.281 g/mol
Pediatric Advil
Melting Point
75 - 77 oC
Pediatric Advil
H2O Solubility
0.049 mg/ml
Pediatric Advil
State
Solid
Pediatric Advil
LogP
3.481
Pediatric Advil
Dosage Forms
Tablet; Suspension
Pediatric Advil
Indication
For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia
Pediatric Advil
Pharmacology
Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ibuprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.
Pediatric Advil
Absorption
rapidly absorbed
Pediatric Advil
side effects and Toxicity
Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting; LD50=1255mg/kg(orally in mice)
Pediatric Advil
Patient Information
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, reduce fever,
and treat osteoarthritis, rheumatoid arthritis, and menstrual cramps. Inform your physician if you are pregnant or
nursing. Ibuprofen should not be taken during the last three months of pregnancy. Inform your physician if you use
alcohol chronically. Ibuprofen should not be taken with aspirin products. This medication should be taken with food,
milk or antacids if stomach upset occurs. Ibuprofen may cause dizziness and drowsiness; use caution while driving or
operating hazardous machinery. Ibuprofen may cause increased sensitivity to sunlight. Use sunscreens and wear
protective clothing until degree of sensitivity is determined. Notify your physician if you develop stomach pain,
bloody vomit, bloody or black tarry stools, cloudy urine, trouble breathing, rash or hives.
Pediatric Advil
Organisms Affected
Humans and other mammals