Lidifen
Brand names,
Lidifen
Analogs
Lidifen
Brand Names Mixture
- Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
- Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
Lidifen
Chemical_Formula
C13H18O2
Lidifen
RX_link
http://www.rxlist.com/cgi/generic/ibup.htm
Lidifen
fda sheet
Lidifen
msds (material safety sheet)
Lidifen
Synthesis Reference
Nicholson, Adams; U.S. Pat. 3,228,831 (1966)
Lidifen
Molecular Weight
206.281 g/mol
Lidifen
Melting Point
75 - 77 oC
Lidifen
H2O Solubility
0.049 mg/ml
Lidifen
State
Solid
Lidifen
LogP
3.481
Lidifen
Dosage Forms
Tablet; Suspension
Lidifen
Indication
For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia
Lidifen
Pharmacology
Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ibuprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.
Lidifen
Absorption
rapidly absorbed
Lidifen
side effects and Toxicity
Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting; LD50=1255mg/kg(orally in mice)
Lidifen
Patient Information
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, reduce fever,
and treat osteoarthritis, rheumatoid arthritis, and menstrual cramps. Inform your physician if you are pregnant or
nursing. Ibuprofen should not be taken during the last three months of pregnancy. Inform your physician if you use
alcohol chronically. Ibuprofen should not be taken with aspirin products. This medication should be taken with food,
milk or antacids if stomach upset occurs. Ibuprofen may cause dizziness and drowsiness; use caution while driving or
operating hazardous machinery. Ibuprofen may cause increased sensitivity to sunlight. Use sunscreens and wear
protective clothing until degree of sensitivity is determined. Notify your physician if you develop stomach pain,
bloody vomit, bloody or black tarry stools, cloudy urine, trouble breathing, rash or hives.
Lidifen
Organisms Affected
Humans and other mammals