Brufanic

Brufanic Brand names, Brufanic Analogs

Brufanic Brand Names Mixture

Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)

Brufanic Chemical_Formula

C₁₃H₁₈O₂

Brufanic RX_link

http://www.rxlist.com/cgi/generic/ibup.htm

Brufanic fda sheet

Brufanic FDA

Brufanic msds (material safety sheet)

Brufanic MSDS

Brufanic Synthesis Reference

Nicholson, Adams; U.S. Pat. 3,228,831 (1966)

Brufanic Molecular Weight

206.281 g/mol

Brufanic Melting Point

75 - 77 ^oC

Brufanic H₂O Solubility

0.049 mg/ml

Brufanic State

Solid

Brufanic LogP

3.481

Brufanic Dosage Forms

Tablet; Suspension

Brufanic Indication

For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia

Brufanic Pharmacology

Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ibuprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.

Brufanic Absorption

rapidly absorbed

Brufanic side effects and Toxicity

Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting; LD₅₀=1255mg/kg(orally in mice)

Brufanic Patient Information

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, reduce fever, and treat osteoarthritis, rheumatoid arthritis, and menstrual cramps. Inform your physician if you are pregnant or nursing. Ibuprofen should not be taken during the last three months of pregnancy. Inform your physician if you use alcohol chronically. Ibuprofen should not be taken with aspirin products. This medication should be taken with food, milk or antacids if stomach upset occurs. Ibuprofen may cause dizziness and drowsiness; use caution while driving or operating hazardous machinery. Ibuprofen may cause increased sensitivity to sunlight. Use sunscreens and wear protective clothing until degree of sensitivity is determined. Notify your physician if you develop stomach pain, bloody vomit, bloody or black tarry stools, cloudy urine, trouble breathing, rash or hives.

Brufanic Organisms Affected

Humans and other mammals