Rafen

Rafen Brand names, Rafen Analogs

Rafen Brand Names Mixture

Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)

Rafen Chemical_Formula

C₁₃H₁₈O₂

Rafen RX_link

http://www.rxlist.com/cgi/generic/ibup.htm

Rafen fda sheet

Rafen FDA

Rafen msds (material safety sheet)

Rafen MSDS

Rafen Synthesis Reference

Nicholson, Adams; U.S. Pat. 3,228,831 (1966)

Rafen Molecular Weight

206.281 g/mol

Rafen Melting Point

75 - 77 ^oC

Rafen H₂O Solubility

0.049 mg/ml

Rafen State

Solid

Rafen LogP

3.481

Rafen Dosage Forms

Tablet; Suspension

Rafen Indication

For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia

Rafen Pharmacology

Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ibuprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.

Rafen Absorption

rapidly absorbed

Rafen side effects and Toxicity

Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting; LD₅₀=1255mg/kg(orally in mice)

Rafen Patient Information

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, reduce fever, and treat osteoarthritis, rheumatoid arthritis, and menstrual cramps. Inform your physician if you are pregnant or nursing. Ibuprofen should not be taken during the last three months of pregnancy. Inform your physician if you use alcohol chronically. Ibuprofen should not be taken with aspirin products. This medication should be taken with food, milk or antacids if stomach upset occurs. Ibuprofen may cause dizziness and drowsiness; use caution while driving or operating hazardous machinery. Ibuprofen may cause increased sensitivity to sunlight. Use sunscreens and wear protective clothing until degree of sensitivity is determined. Notify your physician if you develop stomach pain, bloody vomit, bloody or black tarry stools, cloudy urine, trouble breathing, rash or hives.

Rafen Organisms Affected

Humans and other mammals