PharmacyCodes



TOPOTECAN, HYCAMTIN en es it fr

TOPOTECAN, HYCAMTIN Brand names, TOPOTECAN, HYCAMTIN Analogs

TOPOTECAN, HYCAMTIN Brand Names Mixture

  • No information avaliable

TOPOTECAN, HYCAMTIN Chemical_Formula

C23H23N3O5

TOPOTECAN, HYCAMTIN RX_link

http://www.rxlist.com/cgi/generic2/topotec.htm

TOPOTECAN, HYCAMTIN fda sheet

TOPOTECAN,_HYCAMTIN FDA

TOPOTECAN, HYCAMTIN msds (material safety sheet)

TOPOTECAN,_HYCAMTIN MSDS

TOPOTECAN, HYCAMTIN Synthesis Reference

No information avaliable

TOPOTECAN, HYCAMTIN Molecular Weight

421.446 g/mol

TOPOTECAN, HYCAMTIN Melting Point

213-218 oC

TOPOTECAN, HYCAMTIN H2O Solubility

1 mg/ml

TOPOTECAN, HYCAMTIN State

Solid

TOPOTECAN, HYCAMTIN LogP

1.21

TOPOTECAN, HYCAMTIN Dosage Forms

Powder for solution

TOPOTECAN, HYCAMTIN Indication

For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.

TOPOTECAN, HYCAMTIN Pharmacology

Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.

TOPOTECAN, HYCAMTIN Absorption

No information avaliable

TOPOTECAN, HYCAMTIN side effects and Toxicity

The primary anticipated complication of overdosage would consist of bone marrow suppression.

TOPOTECAN, HYCAMTIN Patient Information

No information avaliable

TOPOTECAN, HYCAMTIN Organisms Affected

Humans and other mammals