Hycamptamine
Hycamptamine Brand names, Hycamptamine Analogs
Hycamptamine Brand Names Mixture
- No information avaliable
Hycamptamine Chemical_Formula
C23H23N3O5
Hycamptamine RX_link
http://www.rxlist.com/cgi/generic2/topotec.htm
Hycamptamine fda sheet
Hycamptamine msds (material safety sheet)
Hycamptamine Synthesis Reference
No information avaliable
Hycamptamine Molecular Weight
421.446 g/mol
Hycamptamine Melting Point
213-218 oC
Hycamptamine H2O Solubility
1 mg/ml
Hycamptamine State
Solid
Hycamptamine LogP
1.21
Hycamptamine Dosage Forms
Powder for solution
Hycamptamine Indication
For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.
Hycamptamine Pharmacology
Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.
Hycamptamine Absorption
No information avaliable
Hycamptamine side effects and Toxicity
The primary anticipated complication of overdosage would consist of bone marrow suppression.
Hycamptamine Patient Information
No information avaliable
Hycamptamine Organisms Affected
Humans and other mammals
