TPT en es it fr

TPT Brand names, TPT Analogs

TPT Brand Names Mixture

  • No information avaliable

TPT Chemical_Formula


TPT RX_link

TPT fda sheet


TPT msds (material safety sheet)


TPT Synthesis Reference

No information avaliable

TPT Molecular Weight

421.446 g/mol

TPT Melting Point

213-218 oC

TPT H2O Solubility

1 mg/ml

TPT State




TPT Dosage Forms

Powder for solution

TPT Indication

For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.

TPT Pharmacology

Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.

TPT Absorption

No information avaliable

TPT side effects and Toxicity

The primary anticipated complication of overdosage would consist of bone marrow suppression.

TPT Patient Information

No information avaliable

TPT Organisms Affected

Humans and other mammals