Topotecan Hcl en es it fr

Topotecan Hcl Brand names, Topotecan Hcl Analogs

Topotecan Hcl Brand Names Mixture

  • No information avaliable

Topotecan Hcl Chemical_Formula


Topotecan Hcl RX_link

Topotecan Hcl fda sheet

Topotecan_Hcl FDA

Topotecan Hcl msds (material safety sheet)

Topotecan_Hcl MSDS

Topotecan Hcl Synthesis Reference

No information avaliable

Topotecan Hcl Molecular Weight

421.446 g/mol

Topotecan Hcl Melting Point

213-218 oC

Topotecan Hcl H2O Solubility

1 mg/ml

Topotecan Hcl State


Topotecan Hcl LogP


Topotecan Hcl Dosage Forms

Powder for solution

Topotecan Hcl Indication

For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.

Topotecan Hcl Pharmacology

Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.

Topotecan Hcl Absorption

No information avaliable

Topotecan Hcl side effects and Toxicity

The primary anticipated complication of overdosage would consist of bone marrow suppression.

Topotecan Hcl Patient Information

No information avaliable

Topotecan Hcl Organisms Affected

Humans and other mammals