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Hycamtin Brand names, Hycamtin Analogs

Hycamtin Brand Names Mixture

  • No information avaliable

Hycamtin Chemical_Formula


Hycamtin RX_link


Hycamtin fda sheet

Hycamtin FDA

Hycamtin msds (material safety sheet)

Hycamtin MSDS

Hycamtin Synthesis Reference

No information avaliable

Hycamtin Molecular Weight

421.446 g/mol

Hycamtin Melting Point

213-218 oC

Hycamtin H2O Solubility

1 mg/ml

Hycamtin State


Hycamtin LogP


Hycamtin Dosage Forms

Powder for solution

Hycamtin Indication

For the treatment of metastatic carcinoma of the ovary and small cell lung cancer following the failure of first-line chemotherapy.

Hycamtin Pharmacology

Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.

Hycamtin Absorption

No information avaliable

Hycamtin side effects and Toxicity

The primary anticipated complication of overdosage would consist of bone marrow suppression.

Hycamtin Patient Information

No information avaliable

Hycamtin Organisms Affected

Humans and other mammals