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Sulfametopyrazine Brand names, Sulfametopyrazine Analogs

Sulfametopyrazine Brand Names Mixture

  • No information avaliable

Sulfametopyrazine Chemical_Formula

C11H12N4O3S

Sulfametopyrazine RX_link

No information avaliable

Sulfametopyrazine fda sheet

Sulfametopyrazine msds (material safety sheet)

Sulfametopyrazine Synthesis Reference

No information avaliable

Sulfametopyrazine Molecular Weight

280.304 g/mol

Sulfametopyrazine Melting Point

169.5 oC

Sulfametopyrazine H2O Solubility

4030 mg/L

Sulfametopyrazine State

Solid

Sulfametopyrazine LogP

1.441

Sulfametopyrazine Dosage Forms

Tablet

Sulfametopyrazine Indication

For the treatment of urinary tract infection and chronic bronchitis.

Sulfametopyrazine Pharmacology

Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfametopyrazine Absorption

No information avaliable

Sulfametopyrazine side effects and Toxicity

No information avaliable

Sulfametopyrazine Patient Information

Sulfametopyrazine Organisms Affected

Gram negative, positive bacteria and plasmodium