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Sulfamethoxypyrazine Brand names, Sulfamethoxypyrazine Analogs

Sulfamethoxypyrazine Brand Names Mixture

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Sulfamethoxypyrazine Chemical_Formula


Sulfamethoxypyrazine RX_link

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Sulfamethoxypyrazine fda sheet

Sulfamethoxypyrazine msds (material safety sheet)

Sulfamethoxypyrazine Synthesis Reference

No information avaliable

Sulfamethoxypyrazine Molecular Weight

280.304 g/mol

Sulfamethoxypyrazine Melting Point

169.5 oC

Sulfamethoxypyrazine H2O Solubility

4030 mg/L

Sulfamethoxypyrazine State


Sulfamethoxypyrazine LogP


Sulfamethoxypyrazine Dosage Forms


Sulfamethoxypyrazine Indication

For the treatment of urinary tract infection and chronic bronchitis.

Sulfamethoxypyrazine Pharmacology

Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfamethoxypyrazine Absorption

No information avaliable

Sulfamethoxypyrazine side effects and Toxicity

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Sulfamethoxypyrazine Patient Information

Sulfamethoxypyrazine Organisms Affected

Gram negative, positive bacteria and plasmodium