Sulfamethoxypyrazine
Sulfamethoxypyrazine Brand names, Sulfamethoxypyrazine Analogs
- Dalysep
- Farmitalia 204/122
- Kelfizin
- Kelfizina
- Kelfizine
- Kelfizine W
- Longum
- Polycidal
- SMP
- SMP2
- Solfametopirazina [Dcit]
- Sulfalen
- Sulfalene
- Sulfalene [Usan:Inn]
- Sulfaleno [Inn-Spanish]
- Sulfalenum [Inn-Latin]
- Sulfamethopyrazine
- Sulfamethoxypyrazine
- Sulfamethoxysuccinate
- Sulfametoxypyridazin
- Sulfapyrazinemethoxine
- Sulfapyrazinemethoxyine
- Sulfapyrazinemethoxyne
Sulfamethoxypyrazine Brand Names Mixture
- No information avaliable
Sulfamethoxypyrazine Chemical_Formula
C11H12N4O3S
Sulfamethoxypyrazine RX_link
No information avaliable
Sulfamethoxypyrazine fda sheet
Sulfamethoxypyrazine msds (material safety sheet)
Sulfamethoxypyrazine Synthesis Reference
No information avaliable
Sulfamethoxypyrazine Molecular Weight
280.304 g/mol
Sulfamethoxypyrazine Melting Point
169.5 oC
Sulfamethoxypyrazine H2O Solubility
4030 mg/L
Sulfamethoxypyrazine State
Solid
Sulfamethoxypyrazine LogP
1.441
Sulfamethoxypyrazine Dosage Forms
Tablet
Sulfamethoxypyrazine Indication
For the treatment of urinary tract infection and chronic bronchitis.
Sulfamethoxypyrazine Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfamethoxypyrazine Absorption
No information avaliable
Sulfamethoxypyrazine side effects and Toxicity
No information avaliable
Sulfamethoxypyrazine Patient Information
Sulfamethoxypyrazine Organisms Affected
Gram negative, positive bacteria and plasmodium
