Sulfalen
Brand names,
Sulfalen
Analogs
Sulfalen
Brand Names Mixture
Sulfalen
Chemical_Formula
C11H12N4O3S
Sulfalen
RX_link
No information avaliable
Sulfalen
fda sheet
Sulfalen
msds (material safety sheet)
Sulfalen
Synthesis Reference
No information avaliable
Sulfalen
Molecular Weight
280.304 g/mol
Sulfalen
Melting Point
169.5 oC
Sulfalen
H2O Solubility
4030 mg/L
Sulfalen
State
Solid
Sulfalen
LogP
1.441
Sulfalen
Dosage Forms
Tablet
Sulfalen
Indication
For the treatment of urinary tract infection and chronic bronchitis.
Sulfalen
Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfalen
Absorption
No information avaliable
Sulfalen
side effects and Toxicity
No information avaliable
Sulfalen
Patient Information
Sulfalen
Organisms Affected
Gram negative, positive bacteria and plasmodium