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Sulfamethopyrazine Brand names, Sulfamethopyrazine Analogs

Sulfamethopyrazine Brand Names Mixture

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Sulfamethopyrazine Chemical_Formula


Sulfamethopyrazine RX_link

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Sulfamethopyrazine fda sheet

Sulfamethopyrazine msds (material safety sheet)

Sulfamethopyrazine Synthesis Reference

No information avaliable

Sulfamethopyrazine Molecular Weight

280.304 g/mol

Sulfamethopyrazine Melting Point

169.5 oC

Sulfamethopyrazine H2O Solubility

4030 mg/L

Sulfamethopyrazine State


Sulfamethopyrazine LogP


Sulfamethopyrazine Dosage Forms


Sulfamethopyrazine Indication

For the treatment of urinary tract infection and chronic bronchitis.

Sulfamethopyrazine Pharmacology

Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfamethopyrazine Absorption

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Sulfamethopyrazine side effects and Toxicity

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Sulfamethopyrazine Patient Information

Sulfamethopyrazine Organisms Affected

Gram negative, positive bacteria and plasmodium