Sulfamethopyrazine
Sulfamethopyrazine Brand names, Sulfamethopyrazine Analogs
- Dalysep
- Farmitalia 204/122
- Kelfizin
- Kelfizina
- Kelfizine
- Kelfizine W
- Longum
- Polycidal
- SMP
- SMP2
- Solfametopirazina [Dcit]
- Sulfalen
- Sulfalene
- Sulfalene [Usan:Inn]
- Sulfaleno [Inn-Spanish]
- Sulfalenum [Inn-Latin]
- Sulfamethopyrazine
- Sulfamethoxypyrazine
- Sulfamethoxysuccinate
- Sulfametoxypyridazin
- Sulfapyrazinemethoxine
- Sulfapyrazinemethoxyine
- Sulfapyrazinemethoxyne
Sulfamethopyrazine Brand Names Mixture
- No information avaliable
Sulfamethopyrazine Chemical_Formula
C11H12N4O3S
Sulfamethopyrazine RX_link
No information avaliable
Sulfamethopyrazine fda sheet
Sulfamethopyrazine msds (material safety sheet)
Sulfamethopyrazine Synthesis Reference
No information avaliable
Sulfamethopyrazine Molecular Weight
280.304 g/mol
Sulfamethopyrazine Melting Point
169.5 oC
Sulfamethopyrazine H2O Solubility
4030 mg/L
Sulfamethopyrazine State
Solid
Sulfamethopyrazine LogP
1.441
Sulfamethopyrazine Dosage Forms
Tablet
Sulfamethopyrazine Indication
For the treatment of urinary tract infection and chronic bronchitis.
Sulfamethopyrazine Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfamethopyrazine Absorption
No information avaliable
Sulfamethopyrazine side effects and Toxicity
No information avaliable
Sulfamethopyrazine Patient Information
Sulfamethopyrazine Organisms Affected
Gram negative, positive bacteria and plasmodium
