Kelfizina
Brand names,
Kelfizina
Analogs
Kelfizina
Brand Names Mixture
Kelfizina
Chemical_Formula
C11H12N4O3S
Kelfizina
RX_link
No information avaliable
Kelfizina
fda sheet
Kelfizina
msds (material safety sheet)
Kelfizina
Synthesis Reference
No information avaliable
Kelfizina
Molecular Weight
280.304 g/mol
Kelfizina
Melting Point
169.5 oC
Kelfizina
H2O Solubility
4030 mg/L
Kelfizina
State
Solid
Kelfizina
LogP
1.441
Kelfizina
Dosage Forms
Tablet
Kelfizina
Indication
For the treatment of urinary tract infection and chronic bronchitis.
Kelfizina
Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Kelfizina
Absorption
No information avaliable
Kelfizina
side effects and Toxicity
No information avaliable
Kelfizina
Patient Information
Kelfizina
Organisms Affected
Gram negative, positive bacteria and plasmodium