Sulfalene
Brand names,
Sulfalene
Analogs
Sulfalene
Brand Names Mixture
Sulfalene
Chemical_Formula
C11H12N4O3S
Sulfalene
RX_link
No information avaliable
Sulfalene
fda sheet
Sulfalene
msds (material safety sheet)
Sulfalene
Synthesis Reference
No information avaliable
Sulfalene
Molecular Weight
280.304 g/mol
Sulfalene
Melting Point
169.5 oC
Sulfalene
H2O Solubility
4030 mg/L
Sulfalene
State
Solid
Sulfalene
LogP
1.441
Sulfalene
Dosage Forms
Tablet
Sulfalene
Indication
For the treatment of urinary tract infection and chronic bronchitis.
Sulfalene
Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfalene
Absorption
No information avaliable
Sulfalene
side effects and Toxicity
No information avaliable
Sulfalene
Patient Information
Sulfalene
Organisms Affected
Gram negative, positive bacteria and plasmodium