Sulfapyrazinemethoxyne
Brand names,
Sulfapyrazinemethoxyne
Analogs
Sulfapyrazinemethoxyne
Brand Names Mixture
Sulfapyrazinemethoxyne
Chemical_Formula
C11H12N4O3S
Sulfapyrazinemethoxyne
RX_link
No information avaliable
Sulfapyrazinemethoxyne
fda sheet
Sulfapyrazinemethoxyne
msds (material safety sheet)
Sulfapyrazinemethoxyne
Synthesis Reference
No information avaliable
Sulfapyrazinemethoxyne
Molecular Weight
280.304 g/mol
Sulfapyrazinemethoxyne
Melting Point
169.5 oC
Sulfapyrazinemethoxyne
H2O Solubility
4030 mg/L
Sulfapyrazinemethoxyne
State
Solid
Sulfapyrazinemethoxyne
LogP
1.441
Sulfapyrazinemethoxyne
Dosage Forms
Tablet
Sulfapyrazinemethoxyne
Indication
For the treatment of urinary tract infection and chronic bronchitis.
Sulfapyrazinemethoxyne
Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfapyrazinemethoxyne
Absorption
No information avaliable
Sulfapyrazinemethoxyne
side effects and Toxicity
No information avaliable
Sulfapyrazinemethoxyne
Patient Information
Sulfapyrazinemethoxyne
Organisms Affected
Gram negative, positive bacteria and plasmodium