Dalysep
Brand names,
Dalysep
Analogs
Dalysep
Brand Names Mixture
Dalysep
Chemical_Formula
C11H12N4O3S
Dalysep
RX_link
No information avaliable
Dalysep
fda sheet
Dalysep
msds (material safety sheet)
Dalysep
Synthesis Reference
No information avaliable
Dalysep
Molecular Weight
280.304 g/mol
Dalysep
Melting Point
169.5 oC
Dalysep
H2O Solubility
4030 mg/L
Dalysep
State
Solid
Dalysep
LogP
1.441
Dalysep
Dosage Forms
Tablet
Dalysep
Indication
For the treatment of urinary tract infection and chronic bronchitis.
Dalysep
Pharmacology
Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Dalysep
Absorption
No information avaliable
Dalysep
side effects and Toxicity
No information avaliable
Dalysep
Patient Information
Dalysep
Organisms Affected
Gram negative, positive bacteria and plasmodium