Selegiline
Selegiline Brand names, Selegiline Analogs
Selegiline Brand Names Mixture
- No information avaliable
Selegiline Chemical_Formula
C13H17N
Selegiline RX_link
http://www.rxlist.com/cgi/generic/seleg.htm
Selegiline fda sheet
Selegiline msds (material safety sheet)
Selegiline Synthesis Reference
Torok Z et al., Acta Pharm Hung. 1992 Sep;62(5):201-11
Selegiline Molecular Weight
187.281 g/mol
Selegiline Melting Point
141-142 oC
Selegiline H2O Solubility
No information avaliable
Selegiline State
Solid
Selegiline LogP
2.884
Selegiline Dosage Forms
Tablet
Selegiline Indication
For the adjunct treatment for Parkinson's disease.
Selegiline Pharmacology
Dopamine is an essential chemical that occurs in many parts of the body. It is the premature degradation of dopamine that results in the symptoms of Parkinson's disease. Monoamine oxidase (MAO) is an enzyme which accelerates the breakdown of dopamine. Selegiline can prolong the effects of dopamine in the brain by preventing its breakdown through seletively blocking MAO. It also may prevent the removal of dopamine between nerve endings and enhance release of dopamine from nerve cells.
Selegiline Absorption
Rapidly absorbed from the gastrointestinal tract.
Selegiline side effects and Toxicity
LD50=63 mg/kg (rats, IV)
Selegiline Patient Information
Selegiline Organisms Affected
Humans and other mammals
