Carbex
Brand names,
Carbex
Analogs
Carbex
Brand Names Mixture
Carbex
Chemical_Formula
C13H17N
Carbex
RX_link
http://www.rxlist.com/cgi/generic/seleg.htm
Carbex
fda sheet
Carbex
msds (material safety sheet)
Carbex
Synthesis Reference
Torok Z et al., Acta Pharm Hung. 1992 Sep;62(5):201-11
Carbex
Molecular Weight
187.281 g/mol
Carbex
Melting Point
141-142 oC
Carbex
H2O Solubility
No information avaliable
Carbex
State
Solid
Carbex
LogP
2.884
Carbex
Dosage Forms
Tablet
Carbex
Indication
For the adjunct treatment for Parkinson's disease.
Carbex
Pharmacology
Dopamine is an essential chemical that occurs in many parts of the body. It is the premature degradation of dopamine that results in the symptoms of Parkinson's disease. Monoamine oxidase (MAO) is an enzyme which accelerates the breakdown of dopamine. Selegiline can prolong the effects of dopamine in the brain by preventing its breakdown through seletively blocking MAO. It also may prevent the removal of dopamine between nerve endings and enhance release of dopamine from nerve cells.
Carbex
Absorption
Rapidly absorbed from the gastrointestinal tract.
Carbex
side effects and Toxicity
LD50=63 mg/kg (rats, IV)
Carbex
Patient Information
Carbex
Organisms Affected
Humans and other mammals