Eldepryl
Brand names,
Eldepryl
Analogs
Eldepryl
Brand Names Mixture
Eldepryl
Chemical_Formula
C13H17N
Eldepryl
RX_link
http://www.rxlist.com/cgi/generic/seleg.htm
Eldepryl
fda sheet
Eldepryl
msds (material safety sheet)
Eldepryl
Synthesis Reference
Torok Z et al., Acta Pharm Hung. 1992 Sep;62(5):201-11
Eldepryl
Molecular Weight
187.281 g/mol
Eldepryl
Melting Point
141-142 oC
Eldepryl
H2O Solubility
No information avaliable
Eldepryl
State
Solid
Eldepryl
LogP
2.884
Eldepryl
Dosage Forms
Tablet
Eldepryl
Indication
For the adjunct treatment for Parkinson's disease.
Eldepryl
Pharmacology
Dopamine is an essential chemical that occurs in many parts of the body. It is the premature degradation of dopamine that results in the symptoms of Parkinson's disease. Monoamine oxidase (MAO) is an enzyme which accelerates the breakdown of dopamine. Selegiline can prolong the effects of dopamine in the brain by preventing its breakdown through seletively blocking MAO. It also may prevent the removal of dopamine between nerve endings and enhance release of dopamine from nerve cells.
Eldepryl
Absorption
Rapidly absorbed from the gastrointestinal tract.
Eldepryl
side effects and Toxicity
LD50=63 mg/kg (rats, IV)
Eldepryl
Patient Information
Eldepryl
Organisms Affected
Humans and other mammals