L-Deprenalin
Brand names,
L-Deprenalin
Analogs
L-Deprenalin
Brand Names Mixture
L-Deprenalin
Chemical_Formula
C13H17N
L-Deprenalin
RX_link
http://www.rxlist.com/cgi/generic/seleg.htm
L-Deprenalin
fda sheet
L-Deprenalin
msds (material safety sheet)
L-Deprenalin
Synthesis Reference
Torok Z et al., Acta Pharm Hung. 1992 Sep;62(5):201-11
L-Deprenalin
Molecular Weight
187.281 g/mol
L-Deprenalin
Melting Point
141-142 oC
L-Deprenalin
H2O Solubility
No information avaliable
L-Deprenalin
State
Solid
L-Deprenalin
LogP
2.884
L-Deprenalin
Dosage Forms
Tablet
L-Deprenalin
Indication
For the adjunct treatment for Parkinson's disease.
L-Deprenalin
Pharmacology
Dopamine is an essential chemical that occurs in many parts of the body. It is the premature degradation of dopamine that results in the symptoms of Parkinson's disease. Monoamine oxidase (MAO) is an enzyme which accelerates the breakdown of dopamine. Selegiline can prolong the effects of dopamine in the brain by preventing its breakdown through seletively blocking MAO. It also may prevent the removal of dopamine between nerve endings and enhance release of dopamine from nerve cells.
L-Deprenalin
Absorption
Rapidly absorbed from the gastrointestinal tract.
L-Deprenalin
side effects and Toxicity
LD50=63 mg/kg (rats, IV)
L-Deprenalin
Patient Information
L-Deprenalin
Organisms Affected
Humans and other mammals