Nu-Selegiline
Brand names,
Nu-Selegiline
Analogs
Nu-Selegiline
Brand Names Mixture
Nu-Selegiline
Chemical_Formula
C13H17N
Nu-Selegiline
RX_link
http://www.rxlist.com/cgi/generic/seleg.htm
Nu-Selegiline
fda sheet
Nu-Selegiline
msds (material safety sheet)
Nu-Selegiline
Synthesis Reference
Torok Z et al., Acta Pharm Hung. 1992 Sep;62(5):201-11
Nu-Selegiline
Molecular Weight
187.281 g/mol
Nu-Selegiline
Melting Point
141-142 oC
Nu-Selegiline
H2O Solubility
No information avaliable
Nu-Selegiline
State
Solid
Nu-Selegiline
LogP
2.884
Nu-Selegiline
Dosage Forms
Tablet
Nu-Selegiline
Indication
For the adjunct treatment for Parkinson's disease.
Nu-Selegiline
Pharmacology
Dopamine is an essential chemical that occurs in many parts of the body. It is the premature degradation of dopamine that results in the symptoms of Parkinson's disease. Monoamine oxidase (MAO) is an enzyme which accelerates the breakdown of dopamine. Selegiline can prolong the effects of dopamine in the brain by preventing its breakdown through seletively blocking MAO. It also may prevent the removal of dopamine between nerve endings and enhance release of dopamine from nerve cells.
Nu-Selegiline
Absorption
Rapidly absorbed from the gastrointestinal tract.
Nu-Selegiline
side effects and Toxicity
LD50=63 mg/kg (rats, IV)
Nu-Selegiline
Patient Information
Nu-Selegiline
Organisms Affected
Humans and other mammals